반응 #1608

반응 방정식

6-(4-chlorophenyl)-pyridazinone

phosphorus pentasulfide

→

6-(4-chlorophenyl)-pyridazinthione

수율 187.1%

용매

pyridine

반응 조건

후처리

1. 1
   온도was refluxed for 1 hour
2. 2
   기타evaporated to dryness
3. 3
   추출extracted with 200 ml of ether
4. 4
   추출The ether extract
5. 5
   세척was washed with water (3×100 ml), brine (100 ml)
6. 6
   건조dried over magnesium sulfate
7. 7
   기타evaporated

실험 절차

A mixture of 3.0 g of 6-(4-chlorophenyl)-pyridazinone, 50 ml of dry pyridine and 3.2 g of phosphorus pentasulfide was refluxed for 1 hour, evaporated to dryness and extracted with 200 ml of ether. The ether extract was washed with water (3×100 ml), brine (100 ml), dried over magnesium sulfate and evaporated to yield 3.0 g of 6-(4-chlorophenyl)-pyridazinthione as a yellow solid.

출처