반응 #1596997

반응 방정식

5-aminosalicylic acid

4-(trifluoromethyl)benzyl chloride

→

5-(4-(trifluoromethyl)benzyl)aminosalicylic acid

수율 50.3%

반응 조건

후처리

1. 1
   기타in Synthesis Example 1

실험 절차

By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-(trifluoromethyl)benzyl chloride (760 mg, 3.92 mmole), 510 mg (50% yield) of 5-(4-(trifluoromethyl)benzyl)aminosalicylic acid was obtained as a white solid.:mp>188° C. (decompose).

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