반응 #1596980

반응 방정식

water

2-phenylethylamine

2-fluoronitrobenzene

potassium carbonate

→

orange crystals

수율 98.0%

N-Phenylethyl-2-nitroaniline

수율 98.0%

용매

DMSO

반응 조건

후처리

1. 1
   온도The mixture was then cooled to ambient temperature
2. 2
   기타resulted in the precipitation of a light orange compound
3. 3
   여과The solid was recovered by filtration
4. 4
   기타dried

실험 절차

A mass of 4.8 g (0.04 mol) of 2-phenylethylamine was added dropwise, at ambient temperature, to a mixture of 5.6 g (0.04 mol) of 2-fluoronitrobenzene and 11.06 g (0.08 mol) of anhydrous potassium carbonate in 30 ml of DMSO. The mixture was heated at 100° C. for 3 hours. The mixture was then cooled to ambient temperature and was added to 100 ml of water, which resulted in the precipitation of a light orange compound. The solid was recovered by filtration and dried using a desiccator at reduced pressure. A mass of 9.4 g of orange crystals was obtained with a yield of 98%. The melting point found was coherent with the theoretical value, i.e. 64-66° C.

출처