반응 #159617
ord-9f50c0c70a1044b5ab00b3b845761f4a
반응 방정식
azetidin-3-ol hydrochloride
methyl 2-chloro-5-fluoronicotinate
→
title compound ( D70 )
methyl 5-fluoro-2-(3-hydroxyazetidin-1-yl)nicotinate
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
The title compound (D70) (75 mg) was prepared according to the experimental procedure described in Description 62 starting from azetidin-3-ol hydrochloride (208 mg, 1.89 mmol) and methyl 2-chloro-5-fluoronicotinate (300 mg, 1.58 mmol, commercially available from Adesis#2-482).