반응 #159604

반응 방정식

1-benzhydryl-3-phenoxyazetidine

→

title compound ( D48 )

수율 37.1%

3-phenoxyazetidine

수율 37.1%

용매

ethanol

반응 조건

후처리

1. 1
   여과then filtered off
2. 2
   농축The filtrate was concentrated
3. 3
   기타to obtain a residue which
4. 4
   기타was recrystallized from diethylether

실험 절차

1-benzhydryl-3-phenoxyazetidine (D20) (2.28 g, 7.23 mmol) was dissolved in ethanol (50 ml) and Pd/C (400 mg, w/w 10%) was added. The mixture was heated at 70° C. under hydrogen atmosphere (50 psi) for 18 hours then filtered off. The filtrate was concentrated to obtain a residue which was recrystallized from diethylether to provide the title compound (D48) (400 mg) as a white solid.

출처