반응 #159378

반응 방정식

4-methyl-3-nitrophenol

butyl bromide

sodium carbonate

DMF

→

4-Butoxy-1-methyl-2-nitrobenzene

용매

MTBE

반응 조건

후처리

1. 1
   기타The cooled reaction solution
2. 2
   세척washed twice each with water and sodium hydroxide solution
3. 3
   기타The organic phase was dried
4. 4
   농축concentrated
5. 5
   기타The product with the molecular weight of 209.25 (C11H15NO3) was obtained in this way

실험 절차

A mixture of 4-methyl-3-nitrophenol (10.0 g), butyl bromide (9.4 g), sodium carbonate (6.9 g) and DMF (50 mL) was heated at 80° C. for 7 hours. The cooled reaction solution was diluted with MTBE and washed twice each with water and sodium hydroxide solution. The organic phase was dried and concentrated. The product with the molecular weight of 209.25 (C11H15NO3) was obtained in this way; MS (ESI): 210 (M+H+).

출처