반응 #1590

반응 방정식

p-chlorobenzoylpropionic acid

nitric acid

→

4-chloro-3-nitrobenzoylpropionic acid

반응 조건

후처리

1. 1
   기타slowly portionwise at 0° C
2. 2
   workup.ADDITIONAfter the addition
3. 3
   여과the resulting white solid was suction filtered
4. 4
   세척washed with water until the pH of the washing liquids
5. 5
   기타dried
6. 6
   기타to yield 3-(4-chloro-3-nitrobenzoyl)propionic

실험 절차

To fuming nitric acid (150 ml) was added p-chlorobenzoylpropionic acid (20.0 g), slowly portionwise at 0° C. After the addition was completed the resulting mixture was stirred at 0° C. for 30 minutes and the resulting white solid was suction filtered and washed with water until the pH of the washing liquids was neutral, then dried to yield 3-(4-chloro-3-nitrobenzoyl)propionic add as a white solid (13.0 g).

출처