반응 #158513

ord-4263d8e43d4b4bf193a293b9d71feb6d

반응 방정식

O=C(Cl)c1cccc([N+](=O)[O-])c1
3-nitrobenzoylchloride
CCOC(=O)C1CCNCC1
ethyl isonipecotate
CCOC(=O)C1CCN(C(=O)c2cccc([N+](=O)[O-])c2)CC1
1-[4-(ethoxycarbonyl)piperidinocarbonyl]-3-nitrobenzene
→
CCOC(=O)C1CCN(C(=O)c2cccc(N)c2)CC1
3-[4-(ethoxycarbonyl)piperidinocarbonyl]aniline

반응물

O=C(Cl)c1cccc([N+](=O)[O-])c1
3-nitrobenzoylchloride
CCOC(=O)C1CCNCC1
ethyl isonipecotate
CCOC(=O)C1CCN(C(=O)c2cccc([N+](=O)[O-])c2)CC1
1-[4-(ethoxycarbonyl)piperidinocarbonyl]-3-nitrobenzene

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타were reacted

실험 절차

In like manner to the preparation of 3-(N-morpholinocarbonyl)aniline, 3-nitrobenzoylchloride and ethyl isonipecotate were reacted to prepare 1-[4-(ethoxycarbonyl)piperidinocarbonyl]-3-nitrobenzene which underwent hydrogenation to provide 3-[4-(ethoxycarbonyl)piperidinocarbonyl]aniline.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08822685B2uspto-grants-2014_09