반응 #158015

반응 방정식

tert-butyl 4-(biphenyl-4-yl)-3-(tert-butoxycarbonylamino)butanoate

HCl

1,4-dioxane

→

3-amino-4-biphenyl-4-yl-butyric acid tert-butyl ester hydrochloride

반응 조건

후처리

1. 1
   농축the reaction mixture is concentrated

실험 절차

To tert-butyl 4-(biphenyl-4-yl)-3-(tert-butoxycarbonylamino)butanoate (110 mg, 0.267 mmol), a solution of 4 M HCl in 1,4-dioxane (0.668 ml, 2.67 mmol) is added. After stirring for 1 h, the reaction mixture is concentrated to give crude 3-amino-4-biphenyl-4-yl-butyric acid tert-butyl ester hydrochloride.

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