반응 #157922
ord-7c2b84a7b779425e99164e43cf496820
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1세척The organic phase was washed with saturated NaHCO3 (3×10 mL), dried Na2SO4
- 2농축concentrated in vacuo
실험 절차
Phenyl cyclohexene (50 mg) and thiophene (100 mg) were dissolved in 33% HBr in acetic acid (0.5 mL). The mixture was stirred at room temperature over night. Tlc indicated full conversion of the starting material. Dichloromethane (10 mL) was added. The organic phase was washed with saturated NaHCO3 (3×10 mL), dried Na2SO4 and concentrated in vacuo. The desired product was afforded after flash chromatography (eluent: dichloromethane). Yield: 39 mg. LC/MS purity (UV/MS): 100/90%, Rt 6.22 min. M+1: 243