반응 #1578280

ord-580add60ba9d428898162a9a4efd0fca

반응 방정식

CC(C)(C)C(=O)Nc1c(F)c(F)c(C(F)(F)F)c(F)c1F
CC(C)(C)C(=O)Nc1c(F)
→
CC(C)(CB1OC(C)(C)C(C)(C)O1)C(=O)Nc1c(F)c(F)c(C(F)(F)F)c(F)c1F
CC(C)(CB1OC(C)(C)C(C
수율 67.0%

반응물

CC(C)(C)C(=O)Nc1c(F)c(F)c(C(F)(F)F)c(F)c1F
CC(C)(C)C(=O)Nc1c(F)c(F)c(C(F)
CAS: 1217507-31-7

시약

CC(=O)O.[Pd]
CC(=O)O.[Pd]
CAS: 3375-31-3
O=C(O)O.[K]
O=C(O)O.[K]
CAS: 298-14-6
COc1cc(OC)c2ccccc2n1
COc1cc(OC)c2ccccc2n1
CAS: 40335-00-0
CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C
CC1(C)OB(B2OC(C)(C)C(C)(C)O2)O
CAS: 73183-34-3

용매

CC#N
CC#N
CAS: 75-05-8

반응 조건

온도
80°CELSIUS

출처

DOI: 10.1002/anie.201509996Borylation dataset from Roche