반응 #1578259

ord-622a25f9d0bb46939c3d03a6f775c301

반응 방정식

CC(C)(C)c1ccc(C(=O)NCc2ccccc2)cc1
CC(C)(C)c1ccc(C(=O)N
→
CC(C)(C)c1ccc(C(=O)NCc2ccccc2)c(B2OC(C)(C)C(C)(C)O2)c1
CC(C)(C)c1ccc(C(=O)N
수율 55.0%

반응물

CC(C)(C)c1ccc(C(=O)NCc2ccccc2)cc1
CC(C)(C)c1ccc(C(=O)NCc2ccccc2)
CAS: 101927-55-3

시약

C1=CCCC=CCC1.C1=CCCC=CCC1.C[OH2+].C[OH2+].[Ir].[Ir]
C1=CCCC=CCC1.C1=CCCC=CCC1.C[OH
CAS: 12148-71-9
CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C
CC1(C)OB(B2OC(C)(C)C(C)(C)O2)O
CAS: 73183-34-3
Cc1[nH]c2c(NC(=O)c3ccc(-c4ccccn4)nc3)cccc2c1C
Cc1[nH]c2c(NC(=O)c3ccc(-c4cccc
CAS: 2366213-69-4

용매

C1CCOC1
C1CCOC1
CAS: 109-99-9

반응 조건

온도
60°CELSIUS

실험 절차

Isolated by chromatography using deactivated silica gel and ethyl acetate and petroleum ether (10:1 to 1:1) as the eluent.

출처

DOI: 10.1002/anie.201907366Borylation dataset from Roche