반응 #1578240

ord-123d454a82fe414292780c8b4704f2fa

반응 방정식

CNC(=O)c1ccc(OC)cc1
CNC(=O)c1ccc(OC)cc1
→
CNC(=O)c1ccc(OC)cc1B1OC(C)(C)C(C)(C)O1
CNC(=O)c1ccc(OC)cc1B
수율 64.0%

반응물

CNC(=O)c1ccc(OC)cc1
CNC(=O)c1ccc(OC)cc1
CAS: 3400-22-4

시약

C1=CCCC=CCC1.C1=CCCC=CCC1.C[OH2+].C[OH2+].[Ir].[Ir]
C1=CCCC=CCC1.C1=CCCC=CCC1.C[OH
CAS: 12148-71-9
c1ccc(-c2ccccn2)nc1
c1ccc(-c2ccccn2)nc1
CAS: 366-18-7
CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C
CC1(C)OB(B2OC(C)(C)C(C)(C)O2)O
CAS: 73183-34-3

용매

C1CCOC1
C1CCOC1
CAS: 109-99-9

반응 조건

온도
60°CELSIUS

실험 절차

Isolated by chromatography using deactivated silica gel and ethyl acetate and petroleum ether (10:1 to 1:1) as the eluent.

출처

DOI: 10.1002/anie.201907366Borylation dataset from Roche