반응 #1578233

ord-c18ad94aa18f45c0aaae4d5010cc96ea

반응 방정식

CNC(=O)c1ccccc1
CNC(=O)c1ccccc1
→
CNC(=O)c1ccccc1B1OC(C)(C)C(C)(C)O1
CNC(=O)c1ccccc1B1OC(
수율 63.0%

반응물

CNC(=O)c1ccccc1
CNC(=O)c1ccccc1
CAS: 613-93-4

시약

C1=CCCC=CCC1.C1=CCCC=CCC1.C[OH2+].C[OH2+].[Ir].[Ir]
C1=CCCC=CCC1.C1=CCCC=CCC1.C[OH
CAS: 12148-71-9
CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C
CC1(C)OB(B2OC(C)(C)C(C)(C)O2)O
CAS: 73183-34-3
Cc1[nH]c2c(NC(=O)c3ccc(-c4ccccn4)nc3)cccc2c1C
Cc1[nH]c2c(NC(=O)c3ccc(-c4cccc
CAS: 2366213-69-4

용매

C1CCOC1
C1CCOC1
CAS: 109-99-9

반응 조건

온도
60°CELSIUS

실험 절차

Isolated by chromatography using deactivated silica gel and ethyl acetate and petroleum ether (10:1 to 2:1) as the eluent.

출처

DOI: 10.1002/anie.201907366Borylation dataset from Roche