반응 #1577553

반응 방정식

methyl 6-(2-(4-bromobenzenesulphonylamino)-indan-5-yl)-6-(3-pyridyl)hex-5-enoate

→

6-(2-(4-Bromobenzenesulphonylamino)indan-5-yl)-6-(3-pyridyl)hex-5-enoic acid

용매

ethanol

반응 조건

후처리

1. 1
   온도After cooling the solution
2. 2
   기타is rotary evaporated
3. 3
   세척washed with 30 ml of methylene chloride
4. 4
   기타The precipitate formed
5. 5
   세척is washed
6. 6
   기타dried

실험 절차

3.7 g of methyl 6-(2-(4-bromobenzenesulphonylamino)-indan-5-yl)-6-(3-pyridyl)hex-5-enoate are refluxed for 15 minutes in 30 ml of ethanol and with 1N of 15N sodium hydroxide solution. After cooling the solution is rotary evaporated and the residue is taken up in water and washed with 30 ml of methylene chloride. Then the aqueous phase is adjusted to pH 4 using hydrochloric acid. The precipitate formed is washed and dried.

출처