반응 #157612

ord-6894ae1ee5c54a259c240242f1316eaf

반응 방정식

O=C1CCc2cc([N+](=O)[O-])c(Br)cc21
6-bromo-5-nitro-2,3-dihydro-1H-inden-1-one
SCc1ccccc1
phenylmethanethiol
O=C([O-])[O-].[K+].[K+]
K2CO3
→
O=C1CCc2cc([N+](=O)[O-])c(SCc3ccccc3)cc21
title compound
수율 79.0%
O=C1CCc2cc([N+](=O)[O-])c(SCc3ccccc3)cc21
6-(Benzylthio)-5-nitro-2,3-dihydro-1H-inden-1-one
수율 79.0%

반응물

O=C1CCc2cc([N+](=O)[O-])c(Br)cc21
6-bromo-5-nitro-2,3-dihydro-1H-inden-1-one
SCc1ccccc1
phenylmethanethiol
O=C([O-])[O-].[K+].[K+]
K2CO3

시약

없음

용매

CN(C)C=O
DMF

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Following General Procedure A, the title compound (672 mg, 79%) was prepared from 6-bromo-5-nitro-2,3-dihydro-1H-inden-1-one (1.5 g, 5.86 mmol), phenylmethanethiol (1 ml, 8.79 mmol) and K2CO3 (4.0 g, 29.29 mmol) in DMF (20 ml).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08822530B2uspto-grants-2014_09