반응 #1573905

반응 방정식

2.001c

1-[3-(4-Chloro-benzoylamino)-benzyl]-piperidine-4-carboxylic acid ethyl ester

5-methylnicotinoyl chloride

2.001a

4-Chloro-N-(3-[1,3]dioxolan-2-yl-phenyl)-benzamide

methyl pyrrolidine-3-carboxylate

→

title compound

rac-1-{3-[(5-Methyl-pyridine-3-carbonyl)-amino]-benzyl}-pyrrolidine-3-carboxylic acid

반응 조건

후처리

1. 1
   기타45 min

실험 절차

The title compound is prepared according to the reaction sequence 2.001a-2.001d described above using 5-methylnicotinoyl chloride instead of 4-chlorobenzoyl chloride as in 2.001a and methyl pyrrolidine-3-carboxylate instead of ethyl isonipecotate as in 2.001c: LC-MS A: tR=0. 45 min; [M+H]+=340.14.

출처