반응 #157023

반응 방정식

4-chloro-3-nitrobenzophenone

3-(N-Boc-amino) piperidine

→

tert-butyl 1-(4-benzoyl-2-nitro phenyl)piperidin-3-ylcarbamate

수율 90.0%

용매

NMP

반응 조건

실험 절차

Method 1 was followed using 4-chloro-3-nitrobenzophenone (1.0 eq), 3-(N-Boc-amino) piperidine (1.1 eq), and TEA (2.0 eq) in NMP yielding tert-butyl 1-(4-benzoyl-2-nitro phenyl)piperidin-3-ylcarbamate (90%). LCMS (m/z): 426.2 (MH+); LC Rt=3.49 min.

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