반응 #156962

반응 방정식

3-amino-1-propanol

benzophenone imine

→

desired product

수율 101.3%

3-[(Diphenylmethylene)amino]propan-1-ol

수율 101.3%

용매

dichloromethane

반응 조건

후처리

1. 1
   여과The reaction mixture was filtered
2. 2
   농축the filtrate was concentrated

실험 절차

A solution of 3-amino-1-propanol [Aldrich product # A76400] (2.0 mL, 26 mmol) in dichloromethane (79 mL) was treated with benzophenone imine (4.4 mL, 26 mmol) and stirred at 25° C. for 16 h. The reaction mixture was filtered and the filtrate was concentrated to give the desired product (6.3 g, quantitative) as an oil. This material was used without further purification. LCMS for C16H18NO (M+H)+: m/z=240.2.

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