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(R)-2-(2,5-difluorophenyl)-4,4-difluoropyrrolidine hydrochloride

Ethyl 5-bromopyrazolo[1,5-a]pyridine-3-carboxylate

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title compound

Ethyl 5-(2-(2,5-difluorophenyl)-4,4-difluoropyrrolidin-1-yl)pyrazolo[1,5-a]pyridine-3-carboxylate

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후처리

1. 1
   기타to afford as yellow solid

실험 절차

The title compound (Int-72) was prepared by the method similar to that for Int-84 using (R)-2-(2,5-difluorophenyl)-4,4-difluoropyrrolidine hydrochloride and Ethyl 5-bromopyrazolo[1,5-a]pyridine-3-carboxylate to afford as yellow solid. LCMS (ESI): m/z 408.1 (M+H).

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