반응 #1562

반응 방정식

1-(2-chloro-4-fluoro-5-nitrophenyl)-3-methyl-s-triazine-2,4,6(1H,3H,5H)-trione

hydrogen

→

title product

1-(5-Amino-2-chloro-4-fluorophenyl)-3-methyl-s-triazine

용매

ethyl acetate

반응 조건

후처리

1. 1
   여과The reaction mixture is then filtered
2. 2
   농축concentrated in vacuo

실험 절차

A mixture of 1-(2-chloro-4-fluoro-5-nitrophenyl)-3-methyl-s-triazine-2,4,6(1H,3H,5H)-trione (28.5 g, 0.09 mol) and 5% platinum on activated carbon (1 g) in ethyl acetate is hydrogenated at 55 psi until hydrogen uptake is complete. The reaction mixture is then filtered and concentrated in vacuo to give the title product as a white solid, mp 244°-245° C.

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