반응 #1552095

반응 방정식

3-(3,3-dimethylbut-1-yn-1-yl)aniline

hydrogen

→

3-(3,3-dimethylbutyl)cyclohexanamine

용매

tetrahydrofuran

반응 조건

후처리

1. 1
   여과the catalyst is filtered off through kieselguhr
2. 2
   농축the product is concentrated under reduced pressure

실험 절차

0.5 g of Ru/C 5% is added to a solution consisting of 1.04 g (0.6 mol) of 3-(3,3-dimethylbut-1-yn-1-yl)aniline in 20 ml of tetrahydrofuran, and the mixture is hydrogenated with 100 bar of hydrogen at 120° C. for 40 hours. After cooling to room temperature, the catalyst is filtered off through kieselguhr and the product is concentrated under reduced pressure. This gives 0.9 g (81% of theory) of 3-(3,3-dimethylbutyl)cyclohexanamine as main component according to MSD-HPLC.

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