반응 #1552050

반응 방정식

1,8-octanediamine

triethylamine

furoyl chloride

→

N,N′-(octane-1,8-diyl)bis(furan-2-carboxamide)

반응 조건

후처리

1. 1
   기타The resulting compound was purified by column chromatography (98:2 DCM:EtOAc)
2. 2
   기타the product obtained as a white solid (21.5 g/92%)

실험 절차

The general procedure was carried out using 1,8-octanediamine (10.0 g, 69.3 mmol), triethylamine (14.2 g, 141 mmol), DMAP (0.17 g, 1.35 mmol) and furoyl chloride (19.0 g, 146 mmol). The resulting compound was purified by column chromatography (98:2 DCM:EtOAc), and the product obtained as a white solid (21.5 g/92%).

출처