반응 #1541933
ord-d54caf9591924161af5917e920c0a530
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1추출the mixture was extracted with chloroform (2×25 ml)
- 2건조by drying over MgSO4
- 3기타The removal of the solvent
- 4기타on a rotary evaporator under reduced pressure
실험 절차
Into a solution of potassium salt of 3-oxo-2-cyanopropanoic acid ethyl ester (1.79 g, 10 mmol) in water (10 ml) was added a 50% solution of triphenylsulfonium chloride in water (5.96 g, 10 mmol). The reaction mixture turned cloudy. Water (15 ml) was added and the mixture was extracted with chloroform (2×25 ml) followed by drying over MgSO4. The removal of the solvent on a rotary evaporator under reduced pressure gave desired product as yellow crystalline material. Yield 3.2 g (80%).