반응 #1537285

반응 방정식

4-t-Butoxy-2,5,6-trifluoro-3-methylpyridine

dibenzylamine

→

4-t-Butoxy-6-dibenzylamino-2,5-difluoro-3-methylpyridine

용매

ethanol

반응 조건

후처리

1. 1
   온도at reflux temperature
2. 2
   기타Solvent is removed
3. 3
   workup.DISSOLUTIONthe residue is dissolved in methylene chloride
4. 4
   세척washed with water
5. 5
   기타The product is purified by column chromatography

실험 절차

4-t-Butoxy-2,5,6-trifluoro-3-methylpyridine from Step 253c above is reacted with dibenzylamine in ethanol at reflux temperature. Solvent is removed, and the residue is dissolved in methylene chloride and washed with water. The product is purified by column chromatography.

출처