반응 #1519116

반응 방정식

(2S,3R)-3-(2-butenyl)-2-hydroxysuccinic dimethyl ester

→

(2S,3R)-3-(n-butyl)-2-hydroxysuccinic dimethyl ester

용매

EtOAc

반응 조건

후처리

1. 1
   여과The suspension is filtered through Celite
2. 2
   세척washed with EtOAc (3×)
3. 3
   농축concentrated in vacuo

실험 절차

To (2S,3R)-3-(2-butenyl)-2-hydroxysuccinic dimethyl ester B-2 (2.5 g) in EtOAc (50 mL) is added 10% Pd/C (0.25 g) and the reaction stirred under a hydrogen atmosphere for 20 hours. The suspension is filtered through Celite, washed with EtOAc (3×) and then concentrated in vacuo to afford (2S,3R)-3-(n-butyl)-2-hydroxysuccinic dimethyl ester B-3.

출처