반응 #1519094

반응 방정식

4-Benzyloxybenzyl chloride

triphenyl phosphine

ether

→

4-benzyloxybenzyltriphenyl phosphonium chloride

용매

toluene

반응 조건

후처리

1. 1
   여과The precipitated phosphonium salt was collected by filtration
2. 2
   세척rinsed with ether and air
3. 3
   기타dried

실험 절차

4-Benzyloxybenzyl chloride (1 g, 0.0043 moles) and triphenyl phosphine (1.127 g, 1 equivalent) in anhydrous toluene (20 mL) were refluxed under nitrogen for ˜8-10 hours. A white precipitate appeared in the reaction mixture. The reaction mixture was then cooled to room temperature and ether (100 mL) was added. The precipitated phosphonium salt was collected by filtration, rinsed with ether and air dried. Yield=0.55 g (25%). MALDI-TOF MS 459.51 obs. (459.54 calc.).

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