반응 #1483084

반응 방정식

Oleoyl chloride

2,2,2-trifluoroethanol

HCl

→

2,2,2-trifluoroethyl oleate

수율 96.1%

반응 조건

후처리

1. 1
   기타excess trifluoroethanol is removed in vacuo
2. 2
   workup.DISTILLATIONVacuum distillation of the residue

실험 절차

Oleoyl chloride (75 g, 250 mmol) is heated at reflux with 2,2,2-trifluoroethanol (60 g, 600 mmol) for 16 hrs. After the evolution of HCl ceased, excess trifluoroethanol is removed in vacuo. Vacuum distillation of the residue afforded 87.6 g of 2,2,2-trifluoroethyl oleate as colorless liquid, by 150°/0.3.

출처