반응 #1478584
ord-e8300acfe5a44cfebc4d75f95493ba60
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타in further process steps, the racemic mixture is separated
- 2기타D-pantolactone is subjected to a condensation reaction with β-alanine
실험 절차
Pantothenic acid can be prepared by chemical synthesis, or biotechnologically by fermentation of suitable microorganisms in suitable nutrient solutions. In the chemical synthesis, DL-pantolactone is an important precursor. It is prepared in a multi-stage process from formaldehyde, isobutylaldehyde and cyanide, and in further process steps, the racemic mixture is separated, D-pantolactone is subjected to a condensation reaction with β-alanine, and D-pantothenic acid is obtained in this way.