반응 #1471265

반응 방정식

triethylamine

3-pyrrolecarboxylic acid

β-alanine benzyl ester p-toluenesulfonate

diethyl phosphorocyanidate

→

title compound

수율 88.6%

benzyl 3-(3-pyrrolecarboxamido)propionate

수율 88.6%

용매

DMF

반응 조건

실험 절차

Using 1.67 g (15 mmol) of 3-pyrrolecarboxylic acid, 6.33 g (18 mmol) of β-alanine benzyl ester p-toluenesulfonate, 2.94 g (18 mmol) of diethyl phosphorocyanidate, 3.64 g (36 mmol) of triethylamine and 50 ml of DMF, 3.62 g of the title compound were obtained in a similar manner as in Example 1 (yield: 89%).

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