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3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-vinylphenyl]propanoic acid, hydrochloride

4-[4-[2-(N-dodecyl-N-methylamino)ethoxy]phenyl]-1,1,1-trifluoro-2-butanone

→

title compound

수율 54.0%

4-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-vinylphenyl]-1,1,1-trifluoro-2-butanone

수율 54.0%

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후처리

1. 1
   기타The residue was chromatographed on silica gel (ethyl acetate)

실험 절차

3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-vinylphenyl]propanoic acid, hydrochloride (830 mg, 1.83 mmol) was reacted by the general procedure as described in the preparation of 4-[4-[2-(N-dodecyl-N-methylamino)ethoxy]phenyl]-1,1,1-trifluoro-2-butanone. The residue was chromatographed on silica gel (ethyl acetate) to afforded the title compound (0.46 g, 54%) as a pale purple oil.

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