반응 #1471087

ord-15227df153254fbfaf506efa93d6c0d4

반응 방정식

C=Cc1cc(OCCN(C)CCCCCCCCCCCC)ccc1CCC(=O)OC
3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-vinylphenyl]propanoic acid, methyl ester
CCCCCCCCCCCCN(C)CCOc1ccc(CCC(=O)O)cc1.Cl
3-[4-[2-(N-dodecyl-N-methylamino)ethoxy]phenyl]propanoic acid, hydrochloride
→
C=Cc1cc(OCCN(C)CCCCCCCCCCCC)ccc1CCC(=O)O.Cl
title compound
수율 93.0%
C=Cc1cc(OCCN(C)CCCCCCCCCCCC)ccc1CCC(=O)O.Cl
3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-vinylphenyl]propanoic acid, hydrochloride
수율 93.0%

반응물

C=Cc1cc(OCCN(C)CCCCCCCCCCCC)ccc1CCC(=O)OC
3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-vinylphenyl]propanoic acid, methyl ester
CCCCCCCCCCCCN(C)CCOc1ccc(CCC(=O)O)cc1.Cl
3-[4-[2-(N-dodecyl-N-methylamino)ethoxy]phenyl]propanoic acid, hydrochloride

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-vinylphenyl]propanoic acid, methyl ester (178 mg, 0.412 mmol) was saponified as described in the preparation of 3-[4-[2-(N-dodecyl-N-methylamino)ethoxy]phenyl]propanoic acid, hydrochloride and afforded the title compound (175 mg, 93%) as a clear oil.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06255496B1uspto-grants-2001_07