반응 #1470463

ord-787957dcabd74079aa945a7e3ffb6fdc

반응 방정식

O=C(O)CCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
(4-carboxybutyl)triphenylphosphonium bromide
CC(=O)CCCCCCCCCO
11-hydroxy-2-undecanone
CCCCCCCCC/C(C)=C\CCCC(=O)O
5Z-6-methylpentadec-5-enoic acid
수율 107.0%

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

164.6 g (0.37 mol) of (4-carboxybutyl)triphenylphosphonium bromide were suspended in 700 ml of tetrahydrofuran. 101 g (0.9 mol) of potassium t-butylate in 150 ml of tetrahydrofuran were added and then 68 g (0.36 mol) of 11-hydroxy-2-undecanone in 50 ml of tetrahydrofuran were added After usual working up there were obtained 98 g of crude 5Z-6-methylpentadec-5-enoic acid.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06255276B1uspto-grants-2001_07