반응 #1470454

반응 방정식

(7-carboxyheptyl)triphenylphosphonium bromide

8-bromooctanal

→

8Z-16-bromohexadec-8-enoic acid

용매

tetrahydrofuran

tetrahydrofuran

반응 조건

후처리

1. 1
   workup.ADDITIONwere added dropwise

실험 절차

48.5 g (0.1 mol) of (7-carboxyheptyl)triphenylphosphonium bromide were suspended in 150 ml of tetrahydrofuran. After the addition of 24.7 g (0.22 mol) of potassium t-butylate in 50 ml of tetrahydrofuran 26.4 g (0.12 mol) of 8-bromooctanal were added dropwise. After the usual work up 35.4 g of crude 8Z-16-bromohexadec-8-enoic acid were obtained having the following characteristics: Z/E=93/6;

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