반응 #1464735

반응 방정식

1-Trifluoroacetylimidazole

4-methyl-2-trimethylsilyloxazole

water

→

title compound

4-Methyl-2-trifluoroacetyloxazole

용매

diethyl ether

반응 조건

후처리

1. 1
   기타The organic phase was separated
2. 2
   기타dried
3. 3
   기타evaporated
4. 4
   기타the residue was purified by flash chromatography

실험 절차

1-Trifluoroacetylimidazole (10 g) was added to a stirred solution of 4-methyl-2-trimethylsilyloxazole (J. Chem. Soc., Chem. Commun., 1984, 258) (9.95 g) in diethyl ether (100 ml) at 0° C. After 20 hours, water was added. The organic phase was separated, dried and evaporated and the residue was purified by flash chromatography to give the title compound as the corresponding hydrate.

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