반응 #1463486

반응 방정식

cyclohexane

4-(4-propylcyclohexyl)cyclohexane

acetone

water

→

3-(4-(4-propylcyclohexyl)cyclohexyl)-2E-propenal

용매

hydrochloric acid

반응 조건

후처리

1. 1
   온도by heating the solution
2. 2
   온도under reflux for 4 hours
3. 3
   추출extracting with ether (50 ml)
4. 4
   건조drying the organic layer over anhydrous magnesium sulfate
5. 5
   농축concentrating under reduced pressure

실험 절차

The resulting cyclohexane derivative was dissolved in a mixed solvent of acetone (80 ml) with 2N hydrochloric acid (8 ml), followed by heating the solution under reflux for 4 hours, cooling the reaction mixture down to room temperature after completion of the stirring, adding water, extracting with ether (50 ml), drying the organic layer over anhydrous magnesium sulfate, and concentrating under reduced pressure to obtain 3-(4-(4-propylcyclohexyl)cyclohexyl)-2E-propenal (3.1 g, 12 mmols). This product was used in the subsequent reaction without any purification.

출처