반응 #1447113
ord-7ba21c1a7b934bf3b41ff8466da5e769
반응 방정식
1-naphthyl dichlorophosphate
L-alanine ethyl ester hydrochloride
Et3N
→
title compound
Ethyl N-[chloro(1-naphthyloxy)phosphoryl]-L-alaninate
용매
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
Following the procedure described for Example 1, step 2, treatment of a solution in DCM (0.144 M) of 1-naphthyl dichlorophosphate with L-alanine ethyl ester hydrochloride (1.0 eq.) and Et3N (2.0 eq.) provided the title compound as a colorless oil as a 1:1.1* mixture of diastereoisomers. 31P NMR (300 MHz, CDCl3) δ: 9.47 and 9.14*.