반응 #1447111

반응 방정식

Et3N

1-naphthol

phosphorus oxychloride

→

title compound

1-Naphthyl dichlorophosphate

용매

Et2O

반응 조건

후처리

1. 1
   workup.WAITthe resulting solution was left
2. 2
   온도to warm to RT overnight
3. 3
   여과The white slurry was filtered under an inert atmosphere
4. 4
   기타all volatiles were removed

실험 절차

To 1-naphthol in Et2O (0.23 M) was added phosphorus oxychloride (1.0 eq.) and the solution was cooled to −78° C. Neat Et3N (1.0 eq) was added and the resulting solution was left to warm to RT overnight. The white slurry was filtered under an inert atmosphere and all volatiles were removed to yield the title compound as a colorless liquid that was used without further purification in the next step. 31P NMR (400 MHz, CDCl3): δ 3.93 ppm.

출처