반응 #1435700

반응 방정식

piperidine

2-(2-tert-butyl-6-methyl-pyran-4-ylidene)-malononitrile

7-dimethylamino-2,3-dihydro-thieno[3,4-b][1,4]dioxine-5-carbaldehyde

→

target compound

수율 48.8%

2-{2-tert-butyl-6-[2-(7-dimethylamino-2,3-dihydro-thieno[3,4-b][1,4]dioxine-5-yl)-vinyl]-pyran-4-ylidene}-malononitrile

수율 48.8%

용매

ethanol

반응 조건

후처리

1. 1
   workup.ADDITIONwas added
2. 2
   온도After cooling the reaction solution
3. 3
   여과the precipitated red solid was filtered
4. 4
   기타recrystallized with ethanol

실험 절차

As shown in the following reaction 1, 2.14 g (10 mmol) of 2-(2-tert-butyl-6-methyl-pyran-4-ylidene)-malononitrile and 2.13 g (10 mmol) of 7-dimethylamino-2,3-dihydro-thieno[3,4-b][1,4]dioxine-5-carbaldehyde were added into 100 ml of ethanol, and 0.93 g (11 mmol) of piperidine was added thereto. The reaction solution was heated at 75° C. for 10 hours. After cooling the reaction solution, the precipitated red solid was filtered, and recrystallized with ethanol to obtain 2 g of the target compound (Yield 48%).

출처