반응 #1435684

반응 방정식

sodium hydroxide

bis(2-chloroethyl) (4-methoxy-5-methyl-1,3-phenylene)biscarbamate

hydrochloric acid

→

3,3′-(4-methoxy-5-methyl-1,3-phenylene)bis(1,3-oxazolidin-2-one)

용매

dioxane

반응 조건

후처리

1. 1
   workup.STIRRINGAfter stirring overnight at room temperature
2. 2
   workup.ADDITIONthe mixture was poured onto ice
3. 3
   여과The precipitated product was filtered off with suction
4. 4
   기타dried overnight under reduced pressure

실험 절차

200 ml of sodium hydroxide solution (20% strength) were initially introduced and heated to 45° C. Subsequently, 59 g of bis(2-chloroethyl) (4-methoxy-5-methyl-1,3-phenylene)biscarbamate were added in portions and the mixture was diluted with 200 ml of dioxane. The mixture was after-stirred for a further 2 h at 45° C. After stirring overnight at room temperature, the mixture was poured onto ice, and the mixture was neutralized with hydrochloric acid. The precipitated product was filtered off with suction and dried overnight under reduced pressure.

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