반응 #1435682

반응 방정식

HCl

2,4-dinitro-6-methylanisole

ethanol

hydrogen

→

2,4-Diamino-6-methylanisole dihydrochloride

용매

water

반응 조건

후처리

1. 1
   온도Subsequently, the mixture was cooled
2. 2
   여과The catalyst was filtered off
3. 3
   기타the filtrate was evaporated to dryness on a rotary evaporator
4. 4
   추출The residue was extracted
5. 5
   여과filtered off
6. 6
   기타dried overnight under reduced pressure

실험 절차

105 g of 2,4-dinitro-6-methylanisole, 1.35 l of ethanol, 150 ml of water and 1 g of Pd/C (5% strength) were initially introduced into the autoclave and hydrogenated at 50° C. with a hydrogen pressure of 50 bar for 12 h. Subsequently, the mixture was cooled and then poured into 1.0 l of semiconcentrated HCl. The catalyst was filtered off, and the filtrate was evaporated to dryness on a rotary evaporator. The residue was extracted by boiling with 2×150 ml of ethanol, filtered off and dried overnight under reduced pressure.

출처