반응 #1379885

반응 방정식

diethanolamine

2-chloro-3-nitro-6-methoxypyridine

dioxane

→

yellow powder

수율 74.0%

2-[(2-hydroxyethyl)(6-methoxy-3-nitro-2-pyridyl)amino]ethanol

수율 74.0%

용매

water

반응 조건

후처리

1. 1
   온도The mixture is refluxed for 2 hours
2. 2
   workup.STIRRINGwith stirring
3. 3
   기타The precipitate formed
4. 4
   여과is filtered off by suction
5. 5
   기타dried

실험 절차

1.9 g (0.01 mol) of the product 2-chloro-3-nitro-6-methoxypyridine, 30 ml of dioxane, 5 ml of water and 2.1 ml (0.02 mol) of diethanolamine are placed in a fully equipped round-bottomed flask. The mixture is refluxed for 2 hours with stirring and is then poured onto an ice/water mixture with stirring. The precipitate formed is filtered off by suction and dried. 1.9 g of yellow powder are obtained, ie a yield of 74%.

출처