반응 #1375813

반응 방정식

methyl 4-tri-n-butylstannylbenzoate

KOH

acetic acid

water

→

title compound

수율 90.3%

4-Tri-n-butylstannylbenzoic acid

수율 90.3%

용매

ethanol

반응 조건

후처리

1. 1
   온도The resulting solution was refluxed for 2 hours
2. 2
   온도The solution was cooled
3. 3
   추출The solution was then extracted with diethyl ether (80 ml)
4. 4
   세척The ether phase was washed with water (30 ml)
5. 5
   건조dried over MgSO4 (5 g)
6. 6
   여과filtered
7. 7
   기타evaporated under reduced pressure

실험 절차

To a solution of methyl 4-tri-n-butylstannylbenzoate (3.0 g, 7 mmol) in absolute ethanol (60 ml) was added 0.25 g KOH (9 mmol). The resulting solution was refluxed for 2 hours. The solution was cooled and poured into an ice-cold solution of acetic acid (0.64 g, 10.6 mmol) and water (100 ml). The solution was then extracted with diethyl ether (80 ml). The ether phase was washed with water (30 ml), dried over MgSO4 (5 g), filtered and evaporated under reduced pressure to afford 2.6 g (88%) of the title compound. This material was used without further purification.

출처