반응 #1375780

ord-c5a9f6850cd0465ba1466b57596eccaf

반응 방정식

CC(=O)C1(O)C=CC=CC1C(=O)Cl
2-acetylsalicyloyl chloride
CCCCCCCC(=O)OCC(O)COC(=O)CCCCCCC
1,3-dioctanoylglycerol
→
CCCCCCCC(=O)OCC(COC(=O)CCCCCCC)OC(=O)C1C=CC=CC1(O)C(C)=O
1,3-dioctanoyl-2-(2-acetylsalicyloyl)glycerol
수율 71.0%

반응물

CC(=O)C1(O)C=CC=CC1C(=O)Cl
2-acetylsalicyloyl chloride
CCCCCCCC(=O)OCC(O)COC(=O)CCCCCCC
1,3-dioctanoylglycerol

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

In analogy with the preceding examples, 2-acetylsalicyloyl chloride is reacted with 1,3-dioctanoylglycerol which, upon work up as before, yields 71% of the desired 1,3-dioctanoyl-2-(2-acetylsalicyloyl)glycerol as an oil.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US03988446uspto-grants-1976_10