반응 #1366316

ord-5e69fe56e7e042fd9f6eb6361228f83f

반응 조건

온도
100°CELSIUS
상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도After cooling it
  2. 2
    추출extracted
  3. 3
    건조The combined organic extracts were dried (MgSO4)
  4. 4
    기타evaporated
  5. 5
    기타to give a white solid
  6. 6
    기타The crude product was recrystallised from diethyl ether

실험 절차

16-Hexadecanolide (5.0 g, 0.02 mol) was added to a mixture of HI (30 g) and acetic acid (20 g). The mixture was heated to 100° C. overnight. After cooling it was poured into a cold sodium thiosulphate solution (150 mL, 10%) and extracted using CH2Cl2. The combined organic extracts were dried (MgSO4) and evaporated to give a white solid. The crude product was recrystallised from diethyl ether. Yield: 4.8 g (64%)

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06447656B1uspto-grants-2002_09