반응 #1359656

반응 방정식

7-(2,6-Dimethyl-phenyl)-benzo[1,2,4]triazin-3-ylamine

sulfamic acid

→

final product

수율 32.0%

[7-(2,6-Dimethyl-phenyl)-benzo[1,2,4]triazin-3-yl]-phenyl-amine

수율 32.0%

용매

aniline

반응 조건

후처리

1. 1
   온도The mixture was reflux overnight

실험 절차

7-(2,6-Dimethyl-phenyl)-benzo[1,2,4]triazin-3-ylamine(24 mg, 0.096 mmol) was dissolved in aniline, sulfamic acid (18 mg, 0.19 mmol) was added. The mixture was reflux overnight. The final product was isolated by preparative HPLC. Yield: 32%. ESI-MS: [M+H]+, 327; 1H NMR (DMSO-d6): δ 2.05(s, 6 H), 7.09(t, J=7.35 Hz, 1 H), 7.18–7.25 (m, 3 H), 7.40(m, 2 H), 7.71(dd, J1=8.5 Hz, J2=1.9 Hz, 1 H), 7.84(d, J=8.5 Hz, 1 H), 8.00(d, J=7.6 Hz, 2 H), 8.11(d, J=1.9 Hz, 1 H).

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