반응 #1351
ord-69d79d7234c34dfc9b1df959b118c003
반응 방정식
ethanolamine
methyl acetoacetate
→
XXIII
수율 91.2%
3-(2-Hydroxyethylamino)-but-2-enoic acid methyl ester
수율 91.2%
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
To an ice-cooled sample of ethanolamine (6.1 g) was added methyl acetoacetate (11.6 g) dropwise. Compound (XXIII 14.5 g) was formed within 30 min (U.S. Pat. No. 1102800).