반응 #1347701

반응 방정식

5-Benzyloxy-2-(2-phenyl-[1,3]dioxan-5-yloxy)pyridine

hydrochloric acid

→

2-(5-Benzyloxypyridin-2-yloxy)propane-1,3-diol

용매

methanol

반응 조건

후처리

1. 1
   농축The methanol was concentrated in vacuo
2. 2
   추출The alkaline solution was extracted with ethyl acetate
3. 3
   농축the organic phase was concentrated

실험 절차

5-Benzyloxy-2-(2-phenyl-[1,3]dioxan-5-yloxy)pyridine was mixed with 20 ml of 4N hydrochloric acid and 20 ml of methanol and stirred at RT for 2 h. The methanol was concentrated in vacuo and the resulting acidic solution was made alkaline with saturated sodium carbonate solution. The alkaline solution was extracted with ethyl acetate, and the organic phase was concentrated.

출처