반응 #1283173

반응 방정식

4-hydroxy-5-methoxy-isophthalaldehyde

PBr3

→

4,5-Dihydroxyisophthalaldehyde

용매

dichloromethane

dichloromethane

반응 조건

후처리

1. 1
   workup.WAITto stand over night at room temperature
2. 2
   기타Dichloromethane was evaporated in vacuo
3. 3
   온도After cooling the product
4. 4
   여과was filtered
5. 5
   세척washed with water

실험 절차

To a suspension containing 1.8 g of 4-hydroxy-5-methoxy-isophthalaldehyde in 20 ml of dichloromethane was added 35 ml of 1 molar PBr3 in dichloromethane. The mixture was allowed to stand over night at room temperature and poured into ice-water. Dichloromethane was evaporated in vacuo. After cooling the product was filtered and washed with water. Yield 0.94 g (57%), m.p. 192°-195° C.

출처