반응 #1271023

반응 방정식

hydrochloride

Paraformaldehyde

p-xylene

1-butyl-3-methylimi-dazolium chloride

→

2,5-dimethylbenzyl chloride

용매

water

water

반응 조건

후처리

1. 1
   온도the temperature is raised to 80˜85° C.
2. 2
   기타The organic layer is transferred into a 250 ml four-neck flask

실험 절차

36.0 g Paraformaldehyde, 84.8 g p-xylene, 14.0 g 1-butyl-3-methylimi-dazolium chloride and 2.4 g concentrated hydrochloric acid whose concentration is 36% are added into a 250 ml four-neck flask and the temperature is raised to 80˜85° C. after well stirring. And the reaction solution is kept warm for 0.5 h after the gas of hydrochloride is inflated, and then cooled to the room temperature, standing for layering. The upper layer is organic layer while the lower layer is water layer. The water layer is dehydrated under vacuum and the gained ionic liquid can be recycled and reused. The organic layer is transferred into a 250 ml four-neck flask and is rectified under vacuum. After desolventizing, 113.4 g 2,5-dimethylbenzyl chloride is finally provided (91.7% yield).

출처